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You may eat or drink these products as part of a regular meal, but do not use them alone when taking ciprofloxacin Moderate Food Interaction Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified foods (e. However, Proquin® XR tablets should be taken with a main meal, preferably the evening meal. However, one of the extended-release ciprofloxacin products, Proquin® XR, should be taken with your main meal of the day. However, avoid dairy produce like milk, cheese and yoghurt, as they can affect how your medicine works. Find them in kefir, yogurt, and even fortified cereals. Cipro can be taken after a large meal or on an empty stomach. Ciprofloxacin tablets and suspension can be taken either with or without food. You may take this medicine with or without food. When you ingest them, they help to make your gut a friendly place for more healthy bacteria to grow. 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